rs2043211 polymorphism in CARD8 is not associated with Tourette syndrome in a family-based association study in the Chinese Han population.

doi:10.1177/0091217415582190

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Article

rs2043211 polymorphism in CARD8 is not associated with Tourette syndrome in a family-based association study in the Chinese Han population.

International journal of psychiatry in medicine - 1 Jan 2015

Yi Mingji, Shao Xiaohui, Ma Jianhua, Tian Bo, Zhang Ying, Liu Shiguo

Abstract excerpt

BACKGROUND: Previous studies showed that postinfectious autoimmunity and immune deficiency played an important role in the pathogenesis of Tourette syndrome. CARD8 can suppress activity of NF-ΚB activated by inflammatory mediators. OBJECTIVE: To study the association between the rs2043211 polymorphism in CARD8 and susceptibility to Tourette syndrome in Chinese Han population. METHODS: We recruited 279 patients...

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PMID: 25921775
DOI: 10.1177/0091217415582190

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CARD8

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