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Article

Circulating interleukin-6 and rheumatoid arthritis: A Mendelian randomization meta-analysis.

Medicine - 1 Jun 2016

Li Bing, Xiao Yu, Xing Dan, Ma Xin-Long, Liu Jun

Abstract excerpt

Interleukin-6 (IL-6), as a pleiotropic cytokine, has been demonstrated to be closely associated with the pathogenisis of rheumatoid arthritis (RA). However, whether this association is causal or not remains unclear, because of the multifactorial role of IL-6 and related confounding factors. We aimed to evaluate the causal relevance between circulating IL-6 levels and the risk of RA through meta-analytical...

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Identifiers

PMID: 27281095
DOI: 10.1097/MD.0000000000003855
PMCID: PMC4907673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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