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Article

Association of IL-6 -174 G>C Polymorphism with Susceptibility to Colorectal Cancer and Gastric Cancer: a Systematic Review and Meta-Analysis.

Acta medica (Hradec Kralove) - 1 Jan 2019

Jafari-Nedooshan Jamal, Dastgheib Seyed Alireza, Kargar Saeed, Zare Mohammad, Raee-Ezzabadi Ali, Heiranizadeh Naeimeh, Sadeghizadeh-Yazdi Jalal, Neamatzadeh Hossein

Abstract excerpt

BACKGROUND: The -174G>C (rs1800795) polymorphism at interleukin 6 (IL-6) gene has been reported to be related with the occurrence of colorectal (CRC) and gastric (GC) cancers. However, the results had been conflicting and controversial. In order to give a comprehensive and precise result, we summarized available data to analyze the association of this polymorphism with CRC and GC risk. METHODS: A comprehensive...

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PMID: 32036845
DOI: 10.14712/18059694.2020.2

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