Article
Significance of genetic variants in DLC1 and their association with hepatocellular carcinoma.
Molecular medicine reports - 1 Sept 2015
Xie Cheng-Rong, Sun Hong-Guang, Sun Yu, Zhao Wen-Xiu, Zhang Sheng, Wang Xiao-Min, Yin Zhen-Yu
Abstract excerpt
DLC1 has been shown to be downregulated or absent in hepatocellular carcinoma (HCC) and is associated with tumorigenesis and development. However, only a small number of studies have focused on genetic variations of DLC1. The present study performed exon sequencing for the DLC1 gene in HCC tissue samples from 105 patients to identify functional genetic variation of DLC1 and its association with HCC...
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