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C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population.

Functional & integrative genomics - 1 Jun 2022

Han Feifei, Qian Lu, Zhang Yi, Liu Ping, Li Rui, Chen Mingwei

Abstract excerpt

BACKGROUND: The mRNA levels of C2CD4A and C2CD4B were dysregulation in lung cancer (LC). We aimed to evaluate the role of C2CD4A/B variants in LC susceptibility. METHODS: There were 710 cases with LC and 710 healthy controls enrolled in the study. The genotyping of twelve variants in C2CD4A/B was carried out by Agena MassARRAY system. Odds ratios (ORs) were calculated by logistic regression analysis to assess the...

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PMID: 35212842
DOI: 10.1007/s10142-022-00827-x

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