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Article

Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics (review).

International journal of oncology - 1 Aug 2012

Zimonjic Drazen B, Popescu Nicholas C

Abstract excerpt

Hepatocellular carcinoma (HCC) is the third leading cause of cancer death, and its incidence is increasing worldwide in an alarming manner. The development of curative therapy for advanced and metastatic HCC is a high clinical priority. The HCC genome is complex and heterogeneous; therefore, the identification of recurrent genomic and related gene alterations is...

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Share to Antineoplastic Combined Chemotherapy Protocols
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Genes, myc

Share to GTPase-Activating Proteins

Share to Liver Neoplasms

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Source

Open in PubMed Open full text

Identifiers

PMID: 22580498
DOI: 10.3892/ijo.2012.1474
PMCID: PMC3583004

Genes

DLC1
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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