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Article

BMP signalling controls the construction of vertebrate mucociliary epithelia

1 Jan 2015

Abstract excerpt

Despite the importance of mucociliary epithelia in animal physiology, the mechanisms controlling their establishment are poorly understood. Using the developing Xenopus epidermis and regenerating human upper airways, we reveal the importance of BMP signalling for the construction of vertebrate mucociliary epithelia. In Xenopus, attenuation of BMP activity is necessary for the specification of multiciliated cells...

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PMID: 26092849
DOI: 10.1242/dev.118679

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