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Article

Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein- and fibroblast growth factor-signaling pathways.

Circulation research - 28 Aug 2009

van Wijk Bram, van den Berg Gert, Abu-Issa Radwan, Barnett Phil, van der Velden Saskia, Schmidt Martina, Ruijter Jan M, Kirby Margaret L, Moorman Antoon F M, van den Hoff Maurice J B

Abstract excerpt

RATIONALE: The epicardium contributes to the majority of nonmyocardial cells in the adult heart. Recent studies have reported that the epicardium is derived from Nkx2.5-positive progenitors and can differentiate into cardiomyocytes. Not much is known about the relation between the myocardial and...

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Identifiers

PMID: 19628790
DOI: 10.1161/CIRCRESAHA.109.203083
PMCID: PMC2861358

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19628790-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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