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Viral genome-capsid core senses host environments to prime RNA release

2021-11-23

Abstract excerpt

<h4>ABSTRACT</h4> Viruses are metastable macromolecular assemblies containing a nucleic acid core packaged by capsid proteins that are primed to disassemble in host-specific environments leading to genome release and replication. The mechanism of how viruses sense environmental changes associated with host entry to prime them for disassembly is unknown. We have applied a combination of mass spectrometry, cryo-EM,...

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Literature Corpus work
55b16fe4-eac8-5897-8e23-25d085a27636
DOI
10.1101/2021.11.23.469659
Open publication

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Viral genome-capsid core senses host environments to prime RNA releaseDOI 10.1101/2021.11.23.469659
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