Article
IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups.
Human immunology - 1 Jul 2015
Elghzaly Ashraf A, Metwally Shereen S, El-Chennawi Farha A, Elgayaar Maha A, Mosaad Youssef M, El-Toraby Ehab E, Hegab Mohsen M, Ibrahim Saleh M
Abstract excerpt
OBJECTIVE: To replicate a single nucleotide polymorphism (SNP) of known genes for lupus (IRF5 rs10488631, PTPN22 rs2476601, BLK rs2736340 and TNFAIP3 rs5029939) and other autoimmune diseases (CD28 rs1980422, IL2RA and KIF5A ) on a newly studied Egyptian cohort to investigate the genetic disparity with different studied ethnic groups in relation to lupus susceptibility. METHODS: 170 Egyptian...