Article
The genetics of systemic lupus erythematosus: understanding how SNPs confer disease susceptibility.
Springer seminars in immunopathology - 1 Oct 2006
Alarcón-Riquelme Marta E
Abstract excerpt
The identification of genes for autoimmune diseases is just the first step towards our understanding of disease pathogenesis. In investigating how mutations, deletions or other types of polymorphic defects occur, it is important to determine the pathways and the mechanisms through which susceptibility leads to disease. In this review I touch on three examples of studies that have attempted to understand the...
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