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Article

Association of interferon regulatory factor 5 (IRF5) markers with an increased risk of lupus and overlapping autoimmunity in a Kuwaiti population.

Annals of human biology - 1 Jan 2000

AlFadhli Suad, Jahabani Iman

Abstract excerpt

BACKGROUND: Variations in IRF5 have been associated with an increased risk of developing lupus (SLE). AIM: To explore the association of IRF5 markers (rs2004640, rs10954213) with susceptibility to SLE and to the development of more than one autoimmune disease (OP) and to analyse the influence of rs2004640 on IRF5 isoform expression. METHODS: A total of 300 age/gender/ethnicity-matched Kuwaitis were screened using...

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PMID: 24697591
DOI: 10.3109/03014460.2014.899623

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