Article
Disease susceptibility genes shared by primary biliary cirrhosis and Crohn's disease in the Japanese population.
Journal of human genetics - 1 Sept 2015
Aiba Yoshihiro, Yamazaki Keiko, Nishida Nao, Kawashima Minae, Hitomi Yuki, Nakamura Hitomi, Komori Atsumasa, Fuyuno Yuta, Takahashi Atsushi, Kawaguchi Takaaki, Takazoe Masakazu, Suzuki Yasuo, Motoya Satoshi, Matsui Toshiyuki, Esaki Motohiro, Matsumoto Takayuki, Kubo Michiaki, Tokunaga Katsushi, Nakamura Minoru
Abstract excerpt
We previously identified TNFSF15 as the most significant susceptibility gene at non-HLA loci for both primary biliary cirrhosis (PBC) and Crohn's diseases (CD) in the Japanese population. The aim of this study is to identify further disease susceptibility genes shared by PBC and CD. We selected 15 and 33 genetic variants that were significantly associated with PBC and CD, respectively, based on previously...
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