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Article

Genome-wide haplotype association analysis of primary biliary cholangitis risk in Japanese.

Scientific reports - 17 May 2018

Im Cindy, Sapkota Yadav, Moon Wonjong, Kawashima Minae, Nakamura Minoru, Tokunaga Katsushi, Yasui Yutaka

Abstract excerpt

Primary biliary cholangitis (PBC) susceptibility loci have largely been discovered through single SNP association testing. In this study, we report genic haplotype patterns associated with PBC risk genome-wide in two Japanese cohorts. Among the 74 genic PBC risk haplotype candidates we detected with a novel methodological approach in a discovery cohort of 1,937 Japanese, nearly two-thirds were replicated (49...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29773854
DOI: 10.1038/s41598-018-26112-1
PMCID: PMC5958065

Genes

TNFSF15
TNFSF8
UMAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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