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Article

[Analysis of disease-pathway by identifying susceptible genes to primary biliary cirrhosis].

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology - 1 Jan 2012

Nakamura Minoru, Makamura Minoru

Abstract excerpt

High concordance rate in monozygotic twins and familial clustering of patients with primary biliary cirrhosis (PBC) indicate the involvement of strong genetic factors in the development of PBC. Recent genome-wide association studies (GWASs) and subsequent meta-analyses in European descent have identified HLA and 21 non-HLA susceptibility loci which are involved in IL12/IL12R signaling, TNF/TLR-NFKB signaling and...

Read the complete abstract on PubMed

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Share to B-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Cirrhosis, Biliary

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Source

Identifiers

PMID: 23291485
DOI: 10.2177/jsci.35.503

Genes

CXCR5
IKZF3
NFKB1
SPIB
STAT4
TNF
TNFAIP2
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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