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Article

Genetic Stabilization of the Drug-Resistant PMEN1 Pneumococcus Lineage by Its Distinctive DpnIII Restriction-Modification System.

mBio - 16 Jun 2015

Eutsey Rory A, Powell Evan, Dordel Janina, Salter Susannah J, Clark Tyson A, Korlach Jonas, Ehrlich Garth D, Hiller N Luisa

Abstract excerpt

UNLABELLED: The human pathogen Streptococcus pneumoniae (pneumococcus) exhibits a high degree of genomic diversity and plasticity. Isolates with high genomic similarity are grouped into lineages that undergo homologous recombination at variable rates. PMEN1 is a pandemic, multidrug-resistant lineage. Heterologous gene exchange between PMEN1 and non-PMEN1 isolates is directional, with extensive gene transfer from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26081630
DOI: 10.1128/mBio.00173-15
PMCID: PMC4471560

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Source receipt: pubmed, retrieved 7 Sept 2026.

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