Article

The Role of Interspecies recombinations in the evolution of antibiotic-resistant pneumococci

2021-02-22

Abstract excerpt

<h4> Abstract </h4> The evolutionary histories of the antibiotic-resistant Streptococcus pneumoniae lineages PMEN3 and PMEN9 were reconstructed using global collections of genomes. In PMEN3, one resistant clade spread worldwide, and underwent 25 serotype switches, enabling evasion of vaccine-induced immunity. In PMEN9, only 9 switches were detected, and multiple resistant lineages emerged independently and circ...

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Literature Corpus work: 29b56c8a-396a-59d0-b48b-103c9c5df1ad
DOI: 10.1101/2021.02.22.432219

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