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Article

Length of the TM3-4 loop of the glycine receptor modulates receptor desensitization.

Neuroscience letters - 23 Jul 2015

Langlhofer G, Janzen D, Meiselbach Heike, Villmann C

Abstract excerpt

Recent studies on the molecular determinants important for glycine receptor biogenesis and function mechanisms indicate an important role of basic residues within the intracellular loop between transmembrane domains (TM) 3 and 4. We investigate the role of loop length and loop exchange in combination with the presence or absence of basic stretches (318)RRKRR and (385)KKIDK of the human glycine receptor α1 using...

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Identifiers

PMID: 26079326
DOI: 10.1016/j.neulet.2015.06.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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