Article
HCV F protein amplifies the predictions of IL-28B and CTLA-4 polymorphisms about the susceptibility and outcomes of HCV infection in Southeast China.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2015
Xiao Wen, Zhang Qi, Deng Xiao Zhao, Jiang Long Feng, Zhu Dan Yan, Pei Jia Ping, Ge Chi Yu, Li Bing Jun, Wang Chang Jun, Zhang Jing Hai, Zhou Zhen Xian, Ding Wei Liang, Xu Xiao Dong, Yue Ming
Abstract excerpt
Cytotoxic T lymphocyte associated antigen-4(CTLA-4) is an inhibitory receptor with great value in the progression of hepatitis C virus (HCV) infection related diseases. To determine the potential associations of IL-28B rs12979860 and CTLA-4 rs231775, rs3087243 and rs5742909 polymorphisms with the generation of HCV F protein, susceptibility and outcomes of HCV infection, a total of 375 healthy controls, 219 HCV...
