Article
Association of IL-28B, TBX21 gene polymorphisms and predictors of virological response for chronic hepatitis C.
Archives of virology - 1 May 2018
Zhu Dan Yan, Deng Xiao Zhao, Zhu Yu Meng, Li Guo Tao, Zhang Guo Qiang, Wang Ling Ju, Zhang Jing Hai, Xiao Wen, Zhou Zhen Xian, Ding Wei Liang
Abstract excerpt
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. The outcomes of both spontaneous HCV clearance and response to therapy depend on both viral and host factors. To investigate the influence of polymorphisms of IL-28B rs12979860 and TBX21 rs17250932, rs4794067 as well as viral factors (HCV genotype, F protein) on the outcome of HCV infection, we genotyped 565 patients with chronic HCV...
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