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Article

Efficient set tests for the genetic analysis of correlated traits.

Nature methods - 1 Aug 2015

Casale Francesco Paolo, Rakitsch Barbara, Lippert Christoph, Stegle Oliver

Abstract excerpt

Set tests are a powerful approach for genome-wide association testing between groups of genetic variants and quantitative traits. We describe mtSet (http://github.com/PMBio/limix), a mixed-model approach that enables joint analysis across multiple correlated traits while accounting for population structure and relatedness. mtSet effectively combines the benefits of set tests with multi-trait modeling and is...

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PMID: 26076425
DOI: 10.1038/nmeth.3439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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