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Article

Association of Polymorphisms in IRAK1, IRAK4 and MyD88, and Severe Invasive Pneumococcal Disease.

The Pediatric infectious disease journal - 1 Sept 2015

Carrasco-Colom Jaume, Jordan Iolanda, Alsina Laia, Garcia-Garcia Juan-José, Cambra-Lasaosa Francisco José, Martín-Mateos María Anunciación, Juan Manel, Muñoz-Almagro Carmen

Abstract excerpt

BACKGROUND: Severe invasive pneumococcal disease (SIPD) has high morbidity and mortality, conditioned by pneumococcus and host factors, such as Toll-like receptors and their Toll-IL1R common signaling pathway. The objectives of this study are (1) to correlate single nucleotide polymorphisms (SNPs) involved in some Toll-IL1R signaling pathway proteins (IRAK1, IRAK4, IRAKM and MyD88) with SIPD by comparing patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26075815
DOI: 10.1097/INF.0000000000000779

Genes

IRAK4
IRAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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