Article
Genetic susceptibility to invasive pneumococcal disease.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2018
Sangil Anna, Arranz María J, Güerri-Fernández Roberto, Pérez Maite, Monzón Helena, Payeras Antoni, Andrés Marta, Torviso Jorge, Ibañez Laura, Garau Javier, Calbo Esther
Abstract excerpt
BACKGROUND: The pathogenesis of IPD remains unknown, especially among middle-aged individuals without risk factors (WRF). OBJECTIVES: The aim of the present study was to investigate the role of single nucleotide polymorphisms (SNP) within key genes involved in innate immune response on IPD susceptibility. METHODS: Forty-three SNPs within 10 immunological genes were investigated in a cohort of 144 Caucasian IPD...
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