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Article

Susceptibility of autoimmune diseases in three polymorphisms of infection-associated gene IRAK1.

Journal of infection in developing countries - 4 Jul 2015

Li Changzheng, Huang Shaohui, Mo Sunlian, Zhang Ning, Zhou Liang, Mao Zhi, Lv Weiran, Li Juan, Zhou Ye

Abstract excerpt

INTRODUCTION: Infection of pathogenic microorganisms is an important reason for autoimmune diseases (ADs). Interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK1) is a key mediator in infection immunity, while the gene of IRAK1 is recognized as a risk gene in ADs. Three single nucleotide polymorphisms (SNPs) in IRAK1 (rs3027898, rs1059702, rs1059703) are considered to be associated with ADs risk. However, the...

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Source

Identifiers

PMID: 26142671
DOI: 10.3855/jidc.6776

Genes

IRAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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