Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Suggested role of silent information regulator 1 (SIRT1) gene in female infertility: A cross-sectional study in Pakistan.

International journal of clinical practice - 1 Jun 2021

Alam Faiza, Rehman Rehana, Fatima Syeda Sadia, Ashraf Mussarat, Khan Taseer Ahmed

Abstract excerpt

AIM & OBJECTIVE: Silent information regulator 1 (SIRT1) gene stimulates the expression of antioxidants and repairs damaged cells. It affects the mitochondrial activity within the oocytes to overcome the oxidant stress. We aimed to assess an association of SIRT1 polymorphism (Tag SNPs rs10509291 and rs12778366) with fertility, and assess serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adolescent
Share to Case-Control Studies
Share to Cross-Sectional Studies
Share to Infertility, Female
Share to Pakistan
Share to Polymorphism, Single Nucleotide
Share to Sirtuin 1
Share to Young Adult

Source

Identifiers

PMID: 33735475
DOI: 10.1111/ijcp.14132

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Suggested role of silent information regulator 1 (SIRT1) gene in female infertility: A cross-sectional study in Pakistan.PMID 33735475Read ↗

Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertilitySemantic proximity Read ↗

Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and AgingSemantic proximity Read ↗

The role of Sirtuin 1 in the pathophysiology of polycystic ovary syndromeSemantic proximity Read ↗

Crosstalk Between Oxidative Stress and Epigenetics: Unveiling New Biomarkers in Human InfertilitySemantic proximity Read ↗

The Silent Threat to Women’s Fertility: Uncovering the Devastating Effects of Oxidative StressSemantic proximity Read ↗

Divergent roles of sirtuin 1 in human granulosa-lutein cells: similarities to human chorionic gonadotropinSemantic proximity Read ↗

Granulosa-Lutein Cell Sirtuin Gene Expression Profiles Differ between Normal Donors and Infertile WomenSemantic proximity Read ↗

The Association of Oxidative Stress and Reactive Oxygen Species Modulator 1 (ROMO1) with Infertility: A Mini ReviewSemantic proximity Read ↗

Research Progress on the Interaction Between SIRT1 and Mitochondrial Biochemistry in the Aging of the Reproductive SystemSemantic proximity Read ↗

SOD1 and SOD2 gene variants are significantly correlated with male infertility in a North Indian population, suggesting a possible pleiotropic conflict.Semantic proximity Read ↗

Sirtuins: Subtle Regulators Involved in Convoluted Mechanisms of PregnancySemantic proximity Read ↗

Improvement of oocyte quality through the SIRT signaling pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.