Article
Association between single nucleotide polymorphisms of MUTYH, hOGG1 and NEIL1 genes, and depression.
Journal of affective disorders - 15 Sept 2015
Czarny Piotr, Kwiatkowski Dominik, Galecki Piotr, Talarowska Monika, Orzechowska Agata, Bobinska Kinga, Bielecka-Kowalska Anna, Szemraj Janusz, Maes Michael, Su Kuan-Pin, Sliwinski Tomasz
Abstract excerpt
BACKGROUND: An elevated levels oxidative modified DNA bases and a decreased efficiency of oxidative DNA damage repair were found in patients with depression disorders, including recurrent type (rDD). The glycosylases are involved in base excision repair (BER), which eliminates oxidative DNA damage. Therefore, we genotyped the single nucleotide polymorphisms (SNPs) of genes encoding three glycosylases: hOGG1,...
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