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Oxidative DNA Damage: A Role in Altering Neuronal Function

12 Sept 2022

Abstract excerpt

. (Oxidative DNA Damage and Cisplatin Neurotoxicity Is Exacerbated by Inhibition of OGG1 Glycosylase Activity and APE1 Endonuclease Activity in Sensory Neurons), inhibition of enzymes that play a role in repairing oxidative DNA damage exacerbated neurotoxic effects of the chemotherapeutic agent, cisplatin. In this Commentary, we aim to expand on the contribution of oxidative DNA damage to other neuropathologies...

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PMID: 36204460
DOI: 10.33696/signaling.3.079

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