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Article

The role of base excision repair in major depressive disorder and bipolar disorder.

Journal of affective disorders - 1 Jun 2022

Kucuker Mehmet Utku, Ozerdem Aysegul, Ceylan Deniz, Cabello-Arreola Alejandra, Ho Ada M C, Joseph Boney, Webb Lauren M, Croarkin Paul E, Frye Mark A, Veldic Marin

Abstract excerpt

BACKGROUND: In vivo and in vitro studies suggest that inflammation and oxidative damage may contribute to the pathogenesis of major depressive disorder (MDD) and bipolar disorder (BD). Imbalance between DNA damage and repair is an emerging research area examining pathophysiological mechanisms of these major mood disorders. This systematic review sought to review DNA repair enzymes, with emphasis on the base...

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Identifiers

PMID: 35306122
DOI: 10.1016/j.jad.2022.03.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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