Article

Oxidative DNA base damage and base excision repair abnormalities in siblings of individuals with bipolar disorder

2023-10-09

Abstract excerpt

<title>Abstract</title> <p>Previous evidence suggests elevated levels of oxidative DNA damage, particularly 8-hydroxy-2'-deoxyguanosine (8-OH-dG), and abnormalities in the repair of 8-OH-dG by the base excision repair (BER) in BD. However, the genetic disposition of these abnormalities remains unknown. In this study, we aimed to investigate the levels of oxidative DNA damage and BER mechanisms in individuals with...

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Literature Corpus work: 671b1347-a2eb-5219-9ced-a3d642e89f2c
DOI: 10.21203/rs.3.rs-3273378/v1

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