Article
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.
The Journal of allergy and clinical immunology - 1 Sept 2022
Eliasen Anders U, Pedersen Casper Emil T, Rasmussen Morten A, Wang Ni, Soverini Matteo, Fritz Amelie, Stokholm Jakob, Chawes Bo L, Morin Andréanne, Bork-Jensen Jette, Grarup Niels, Pedersen Oluf, Hansen Torben, Linneberg Allan, Mortensen Preben B, Hougaard David M, Bybjerg-Grauholm Jonas, Bækvad-Hansen Marie, Mors Ole, Nordentoft Merete, Børglum Anders D, Werge Thomas, Agerbo Esben, Söderhall Cilla, Altman Matthew C, Thysen Anna H, McKennan Chris G, Brix Susanne, Gern James E, Ober Carole, Ahluwalia Tarunveer S, Bisgaard Hans, Pedersen Anders G, Bønnelykke Klaus
Abstract excerpt
BACKGROUND: Asthma with severe exacerbation is one of the most common causes of hospitalization among young children. Exacerbations are typically triggered by respiratory infections, but the host factors causing recurrent infections and exacerbations in some children are poorly understood. As a result, current treatment options and preventive measures are inadequate. OBJECTIVE: We sought to identify genetic...
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