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Genetic variants of H2AX gene were associated with PM2.5-modulated DNA damage levels in Chinese Han populations.

Mutation research - 1 Aug 2015

Sun Chongqi, Chu Minjie, Chen Weihong, Jin Guangfu, Gong Jianhang, Zhu Meng, Yuan Jing, Dai Juncheng, Wang Meilin, Pan Yun, Song Yuanchao, Ding Xiaojie, Du Mulong, Dong Jing, Zhang Zhengdong, Hu Zhibin, Wu Tangchun, Shen Hongbing

Abstract excerpt

Exposure to particulate matter 2.5 (PM2.5) may result in DNA damage. Histone variant H2AX phosphorylation plays a central role in the response to damaged chromatin. In the current study, we investigated whether H2AX gene polymorphisms account for PM2.5-modulated DNA damage levels. A total of 307 healthy urban residents were collected from three cities in southern, central, and northern China, Zhuhai, Wuhan, and...

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PMID: 26073471
DOI: 10.1016/j.mrfmmm.2015.05.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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