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Genetic variants, PM2.5 exposure level and global DNA methylation level: A multi-center population-based study in Chinese.

Toxicology letters - 5 Mar 2017

Liu Jia, Xie Kaipeng, Chen Weihong, Zhu Meng, Shen Wei, Yuan Jing, Cheng Yang, Geng Liguo, Wang Yuzhuo, Li Zhihua, Zhang Jiahui, Jin Guangfu, Dai Juncheng, Ma Hongxia, Du Jiangbo, Wang Meilin, Zhang Zhengdong, Hu Zhibin, Wu Tangchun, Shen Hongbing

Abstract excerpt

Global DNA methylation levels can be determined by environmental and genetic factors. There are emerging evidences that methylation status can be modified as exposed to environmental factors such as PM2.5, but the genetic determinants are still largely unknown. To explore whether genetic variants contribute to global DNA methylation levels with consideration of environmental exposures, we systematically evaluated...

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PMID: 28185982
DOI: 10.1016/j.toxlet.2017.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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