Article
Genetic variants in autophagy associated genes are associated with DNA damage levels in Chinese population.
Gene - 30 Aug 2017
Li Zhihua, Xin Junyi, Chen Weihong, Liu Jia, Zhu Meng, Zhao Congwen, Yuan Jing, Jin Guangfu, Ma Hongxia, Du Jiangbo, Hu Zhibin, Wu Tangchun, Shen Hongbing, Dai Juncheng, Yu Hao
Abstract excerpt
Autophagy associated genes (ATGs) played an important role in the repair process of DNA damage and decreased autophagy may weaken the repair process and aggravate DNA damage. Based on this, we hypothesized that DNA damage levels might be modified by genetic variants in autophagy associated genes. In order to validate our hypothesis, 307 subjects were recruited from three different cities (Zhuhai, Wuhan and...
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