Particulate matter 2.5 induces the skin barrier dysfunction and cutaneous inflammation via AhR ‐ and T helper 17 cell‐related genes in human skin tissue as identified via transcriptome analysis

Abstract excerpt

Particulate matter (PM2.5) is an environmental pollutant causing skin inflammatory diseases via epidermal barrier damage. However, the mechanism and related gene expression induced by PM2.5 remains unclear. Our aim was to determine the effect of PM2.5 on human skin tissue ex vivo, and elucidate the mechanism of T helper 17 cell-related inflammatory cytokine and skin barrier function. We verified the expression...

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