Article
DNMT3A mutation analysis in adult patients with acute lymphoblastic leukemia.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Jun 2015
Liu Ya-Nan, Zhang Na, Wu Ying, Yang Li, Ding Xiao-Yi, Zhou Jian-Feng, Xiao Min
Abstract excerpt
DNA methyl-transferase 3A (DNMT3A) mutation has recently been identified as an independent risk factor for patients with acute myeloid leukemia (AML). However, reports are scanty on its rate and subsequent impact on patients with acute lymphoblastic leukemia (ALL), especially in Chinese population. In this study, we investigated the incidence and prognostic implication of DNMT3A mutation in 57 Chinese adult ALL...
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