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Article

Brain structural and clinical changes after first episode psychosis: Focus on cannabinoid receptor 1 polymorphisms.

Psychiatry research - 30 Aug 2015

Suárez-Pinilla Paula, Roiz-Santiañez Roberto, Ortiz-García de la Foz Víctor, Guest Paul C, Ayesa-Arriola Rosa, Córdova-Palomera Aldo, Tordesillas-Gutierrez Diana, Crespo-Facorro Benedicto

Abstract excerpt

Cannabinoid receptor 1 (CNR1) gene polymorphisms have been associated with central and peripheral effects of cannabis and schizophrenia pathophysiology. Here, we have tested whether three CNR1 variants (rs1049353, rs1535255 and rs2023239) are associated with changes in brain volumes, body mass index (BMI) or psychopathological scores in a 3-year longitudinal study of 65 first-episode psychosis patients. The...

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Source

Identifiers

PMID: 26071625
DOI: 10.1016/j.pscychresns.2015.05.005

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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