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Article

Functional genetic variation of the cannabinoid receptor 1 and cannabis use interact on prefrontal connectivity and related working memory behavior.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2015

Colizzi Marco, Fazio Leonardo, Ferranti Laura, Porcelli Annamaria, Masellis Rita, Marvulli Daniela, Bonvino Aurora, Ursini Gianluca, Blasi Giuseppe, Bertolino Alessandro

Abstract excerpt

Cannabinoid signaling is involved in different brain functions and it is mediated by the cannabinoid receptor 1 (CNR1), which is encoded by the CNR1 gene. Previous evidence suggests an association between cognition and cannabis use. The logical interaction between genetically determined cannabinoid signaling and cannabis use has not been determined. Therefore, we investigated whether CNR1 variation predicts CNR1...

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Identifiers

PMID: 25139064
DOI: 10.1038/npp.2014.213
PMCID: PMC4289952

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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