Article
Effects of cannabis and familial loading on subcortical brain volumes in first-episode schizophrenia.
European archives of psychiatry and clinical neuroscience - 1 Nov 2013
Malchow Berend, Hasan Alkomiet, Schneider-Axmann Thomas, Jatzko Alexander, Gruber Oliver, Schmitt Andrea, Falkai Peter, Wobrock Thomas
Abstract excerpt
Schizophrenia is a severe neuropsychiatric disorder with familial loading as heritable risk factor and cannabis abuse as the most relevant environmental risk factor up to date. Cannabis abuse has been related to an earlier onset of the disease and persisting cannabis consumption is associated with reduced symptom improvement. However, the underlying morphological and biochemical brain alterations due to these...
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