Article
A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 May 2010
Tiwari Arun K, Zai Clement C, Likhodi Olga, Lisker Annika, Singh Deepika, Souza Renan P, Batra Poonam, Zaidi Syed H E, Chen Sheng, Liu Fang, Puls Imke, Meltzer Herbert Y, Lieberman Jeffrey A, Kennedy James L, Müller Daniel J
Abstract excerpt
Antipsychotic-induced weight gain has emerged as a serious complication in the treatment of patients with atypical antipsychotic drugs. The cannabinoid receptor 1 (CNR1) is expressed centrally in the hypothalamic region and associated with appetite and satiety, as well as peripherally. An antagon...
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