MAPK14 and CNR1 gene variant interactions: effects on brain volume deficits in schizophrenia patients with marijuana misuse.

doi:10.1017/S0033291712001559

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Article

MAPK14 and CNR1 gene variant interactions: effects on brain volume deficits in schizophrenia patients with marijuana misuse.

Psychological medicine - 1 Mar 2013

Onwuameze O E, Nam K W, Epping E A, Wassink T H, Ziebell S, Andreasen N C, Ho B-C

Abstract excerpt

BACKGROUND: Adolescent marijuana use is associated with increased risk for schizophrenia. We previously reported that marijuana misuse in conjunction with specific cannabinoid receptor 1 (CNR1) genetic variants (rs12720071-G-allele carriers) contributed to white-matter (WM) brain volume deficits in schizophrenia patients. In this study, we assessed the influence of another cannabinoid-related gene,...

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Identifiers

PMID: 22850347
DOI: 10.1017/S0033291712001559
PMCID: PMC3847818

Genes

MAPK14
CNR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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