Article
Rapid method for growth hormone receptor exon 3 delete (GHRd3) SNP genotyping from archival human placental samples.
Endocrine - 1 Aug 2015
Pelekanos Rebecca A, Sardesai Varda S, Dekker Nitert Marloes, Callaway Leonie K, Fisk Nicholas M, Jeffery Penny L
Abstract excerpt
Analysis of archival samples from cohorts of pregnant women may be key to discovering prognosticators of stillbirth and pregnancy/perinatal complications. Growth hormone (GH) and its receptor (GHR) are pivotal in feto-placental development and pregnancy maintenance. We report a rapid, optimized method for genotyping the GHR full-length versus exon 3-deleted isoform (GHRd3). TaqMan single nucleotide polymorphism...
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