The exon 3 polymorphism of the growth hormone receptor is a severity-related factor for osteoporosis.

doi:10.1007/s12020-013-0004-1

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Article

The exon 3 polymorphism of the growth hormone receptor is a severity-related factor for osteoporosis.

Endocrine - 1 Apr 2014

Marques Felipe Albuquerque, Lins Túlio Cesar, Lima Ricardo Moreno, Fonseca Rômulo Maia Carlos, de França Nanci Maria, de Oliveira Ricardo Jacó, de Oliveira Cardoso Maria Teresinha, Pereira Rinaldo Wellerson, Pogue Robert

Abstract excerpt

The purpose of this study was to investigate the association between the GHR exon 3 fl/d3 polymorphism and body composition traits in Brazilian cohorts of normal post-menarche adolescent girls and in post-menopausal women with and without osteoporosis. First, multiplex PCR and quantitative PCR (TaqMan) were used with 105 DNA samples from the general Brazilian population to validate the SNP rs6873545 as a...

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PMID: 23812803
DOI: 10.1007/s12020-013-0004-1

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