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Human Placental Growth Hormone Variant in Pathological Pregnancies

6 Apr 2018

Abstract excerpt

Growth hormone (GH), an endocrine hormone, primarily secreted from the anterior pituitary, stimulates growth, cell reproduction, and regeneration and is a major regulator of postnatal growth. Humans have two GH genes that encode two versions of GH proteins: a pituitary version (GH-N/GH1) and a placental GH-variant (GH-V/GH2), which are expressed in the syncytiotrophoblast and extravillous trophoblast cells of the...

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PMID: 29659791
DOI: 10.1210/en.2018-00037

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