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Article

Clinical Translationality of KCNJ5 Mutation in Aldosterone Producing Adenoma.

International journal of molecular sciences - 12 Aug 2022

Kitamoto Takumi, Nishikawa Tetsuo

Abstract excerpt

Hypertension due to primary aldosteronism poses a risk of severe cardiovascular complications compared to essential hypertension. The discovery of the KCNJ5 somatic mutation in aldosteroene producing adenoma (APA) in 2011 and the development of specific CYP11B2 antibodies in 2012 have greatly advanced our understanding of the pathophysiology of primary aldosteronism. In particular, the presence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP11B2

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Identifiers

PMID: 36012306
DOI: 10.3390/ijms23169042
PMCID: PMC9409469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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