Article
Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Sept 2015
Albers Peter H, Bojsen-Møller Kirstine N, Dirksen Carsten, Serup Annette K, Kristensen Dorte E, Frystyk Jan, Clausen Trine R, Kiens Bente, Richter Erik A, Madsbad Sten, Wojtaszewski Jørgen F P
Abstract excerpt
Roux-en-Y gastric bypass (RYGB) leads to increased peripheral insulin sensitivity. The aim of this study was to investigate the effect of RYGB on expression and regulation of proteins involved in regulation of peripheral glucose metabolism. Skeletal muscle and adipose tissue biopsies from glucose-tolerant and type 2 diabetic subjects at fasting and during a hyperinsulinemic-euglycemic clamp before as well as 1 wk...
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