Article
Using CellMiner 1.6 for Systems Pharmacology and Genomic Analysis of the NCI-60.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2015
Reinhold William C, Sunshine Margot, Varma Sudhir, Doroshow James H, Pommier Yves
Abstract excerpt
The NCI-60 cancer cell line panel provides a premier model for data integration, and systems pharmacology being the largest publicly available database of anticancer drug activity, genomic, molecular, and phenotypic data. It comprises gene expression (25,722 transcripts), microRNAs (360 miRNAs), whole-genome DNA copy number (23,413 genes), whole-exome sequencing (variants for 16,568 genes), protein levels (94...
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