Article
The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.
Cancer research - 15 Jul 2013
Abaan Ogan D, Polley Eric C, Davis Sean R, Zhu Yuelin J, Bilke Sven, Walker Robert L, Pineda Marbin, Gindin Yevgeniy, Jiang Yuan, Reinhold William C, Holbeck Susan L, Simon Richard M, Doroshow James H, Pommier Yves, Meltzer Paul S
Abstract excerpt
The NCI-60 cell lines are the most frequently studied human tumor cell lines in cancer research. This panel has generated the most extensive cancer pharmacology database worldwide. In addition, these cell lines have been intensely investigated, providing a unique platform for hypothesis-driven research focused on enhancing our understanding of tumor biology. Here, we report a comprehensive analysis of coding...
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