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Article

Cancer driver drug interaction explorer.

Nucleic acids research - 5 Jul 2022

Hartung Michael, Anastasi Elisa, Mamdouh Zeinab M, Nogales Cristian, Schmidt Harald H H W, Baumbach Jan, Zolotareva Olga, List Markus

Abstract excerpt

Cancer is a heterogeneous disease characterized by unregulated cell growth and promoted by mutations in cancer driver genes some of which encode suitable drug targets. Since the distinct set of cancer driver genes can vary between and within cancer types, evidence-based selection of drugs is crucial for targeted therapy following the precision medicine paradigm. However, many putative cancer driver genes can not...

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PMID: 35580047
DOI: 10.1093/nar/gkac384
PMCID: PMC9252786

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