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Article

PTEN loss is a context‐dependent outcome determinant in obese and non‐obese endometrioid endometrial cancer patients

16 May 2015

Abstract excerpt

Endometrial cancer incidence is increasing, due in part to a strong association with obesity. Mutations in the phosphatidylinositol 3-kinase (PI3K) pathway, the central relay pathway of insulin signals, occur in the majority of endometrioid adenocarcinomas, the most common form of endometrial cancer. We sought to determine the impact of PI3K pathway alterations on progression free survival in a cohort of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26045339
DOI: 10.1016/j.molonc.2015.04.014

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