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Article

Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer.

Cancer - 15 Feb 2014

Mackay Helen J, Eisenhauer Elizabeth A, Kamel-Reid Suzanne, Tsao Ming, Clarke Blaise, Karakasis Katherine, Werner Henrica M J, Trovik Jone, Akslen Lars A, Salvesen Helga B, Tu Dongsheng, Oza Amit M

Abstract excerpt

BACKGROUND: Targeting the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway is of increasing interest as a therapeutic strategy in many tumors. The aim of this study was to identify molecular markers associated with mTOR inhibitor activity in women with metasta...

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Identifiers

PMID: 24166148
DOI: 10.1002/cncr.28414

Genes

PTEN
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24166148-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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